Carm1^m9Bei

Eight week old A/J male mice were treated weekly for three weeks with ENU. After several weeks of recovery, mice were crossed to C57BL/6 females with or without a lacZ reporter. Resulting females were backrossed to their fathers and subjected to phenotype screening. The mutation is an C-to-A mutation that changes alanine codon 296 (GCA) to glutamic acid (GAA) (p.A296E). (J:199782)