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A cassette containing an IRES-lacZ followed by an FRT flanked neomycin selection cassette was inserted in exon 3. No beta-galactosidase activity was detected in embryos. Exon 3 is spliced out of mutant transcripts and splicing of exon 2 to exon 4 causes a frameshift creating a premature stop codon. No protein is detectable by Western blot analysis. (J:199559)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
