Cre-mediated cassette exchange replaces the gene trap cassette with a CAG promoter driving ubiquitous expression of a fusion of exons 1 and 2 of Ptf1aos with 456 bp of the Etn2 sequence with the retrotransposon insertion that produces the Etn2Sd phenotype (mGm13336) followed by a polyadenylation sequence and FRT-flanked puromycin resistance cassette. (J:195133)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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