Cre-mediated cassette exchange replaces the gene trap cassette with a CAG promoter driving ubiquitous expression of a fusion of exons 1 and 2 of Ptf1aos with 456 bp of the Etn2 sequence with the retrotransposon insertion that produces the Etn2Sd phenotype (mGm13336) followed by a polyadenylation sequence and FRT-flanked puromycin resistance cassette. (J:195133)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count