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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Ptf1a/Ptf1aos
tm2(Ptf1a)Kymm
Alias:
Gm13336-Ptf1a
Ptf1a
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Basic Information
Phenotypes
References Literature
Recombination of Ptf1a/Ptf1aostm1Kymm exchanged the floxed neomycin resistance cassette with the Ptf1a open reading frame, FRT site, puromycin resistance cassette and lox2272 site. This allele was generated in ES cells containing Etn2Sd. (J:195133)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5502955
Not Specified
Targeted
Insertion, Intragenic deletion
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--
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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