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An existing targeting vector was modified by inserting a codon-improved cre sequence in place of the EGFP sequence in the pFloxRI-C9a-EGFP construct. This construct was electroporated into PRX-B6N (Primogenix) for homologous recombination. Animals carrying the cre allele were crossed to PGK-cre mice to delete the floxed neomycin selection cassette. (J:199355)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
