A floxed PGK/Tn5 neomycin resistance (neo) cassette and the Akv1-99 murine leukemia virus long terminal repeat were inserted into the promoter via homologous recombination. The viral long terminal repeat was inserted at the proviral integration site 3 in the anti-sense direction. Western blot analysis confirms increase protein expression in the thymus and spleen. (J:199340)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion
--
1
21
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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