A loxP site was inserted upstream of the coding exon. An FRT-flanked neomycin (neo) resistance cassette with a loxP site was inserted downstream of the coding exon. Flp-mediated recombination removed the neo cassette and left the coding exon floxed. (J:196306)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count