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The targeting contruct inserted (5' to 3') a wild-type FRT site, splice acceptor site, floxed neomycin resistance/STOP cassette, reverse tetracycline transactivator (rtTA), IRES, puromycin resistance cassette, polyadenylation sequence, tetracycline response element (TRE), a polycistronic Pou5f1, Sox2, Klf4, and Myc transgene, IRES, EGFP, luciferase, polyadenylation sequence, mutated FRT site and promoterless neomycin resistance cassette. (J:195147)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
