A loxP site was inserted in intron 4 and an FRT flanked neomycin selection cassette followed by a second loxP site was inserted in intron 7. The selection cassette was excised from properly targeted mice by flp recombinase. (J:194832)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count