A loxP site was inserted upstream of exon 11. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 15. Cre-mediated recombination removed exons 11 through 15 and the neomycin resistance cassette. (J:198769)
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A loxP site was inserted upstream of exon 11. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 15. Cre-mediated recombination removed exons 11 through 15 and the neomycin resistance cassette. (J:198769)