TALEN targeting of exon 9 for homologous recombination with single stranded oligonucleotides (ssODNs) replaces the deleted nucleotide (C/G) in the retinal degeneration 8 (rd8) mutation and incorporates 5 synonymous base substitutions inside the TALEN binding regions. (J:206789)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
Insertion
--
1
12
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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