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EN
Sequences encoding a cre/ERT2 fusion protein, Frt-flanked neo cassette, and a polyadenylation signal were inserted into a BAC containing the Ucp1 promoter by recombineering methods. The neo marker was not removed, as the original construct showed more efficient cre activity. The purified construct was microinjected into fertilized C57BL/6N oocytes. Line 426 was established. (J:198491)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
