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The targeting construct used has lox recombination sites flanking the splice acceptor of a beta-geo fusion gene that was inserted into intron 1. In the unrecombined state, the presence of the beta-geo fusion gene disrupts expression of the gene. Upon recombination, splicing and expression of the endogenous gene can be restored. (J:196476)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
