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The targeting constructed inserted between exon 1 and 2 contained a floxed splice acceptor neomycin resistance cassette and translation initiation site with 2 polyadenylation sequences followed by a truncated Notch1 cDNA encoding the intracellular domain. Cre-mediated recombination is required to achieve expression of the Notch2 intracellular domain. (J:196407)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
