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Using recombineering methods, a cre/ERT2 cassette was inserted at the ATG codon in exon 1 of the Tff2 gene in the BAC RP24-335C10. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. Three founders positive for the transgene were obtained and F4 or F5 generations were crossed to reporter mice for analyses. The three lines show similar recombination patterns and 2 of these were used to carry out further experiments. (J:198266)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
