An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of the coding sequence. An additional loxP site was inserted 1.5 kb downstream of the translation initiation site. Flp-mediated recombination removed the neomycin resistance cassette and left a portion of the coding sequence floxed. (J:196017)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count