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The CAG promoter drives ubiquitous expression of the transcriptional repressor molecule (tetR) fused to the KRAB domain of human ZNF10 followed by a polyadenylation sequence. This transgene allows for inducible and reversable regulation of an endogenous gene containing the inserted tetracycline response element. Four lines were generated, including line tTS. (J:196015)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
