The construct targeted to the locus contains a floxed neomycin resistance/STOP cassette, the human EIF1AX promoter, a Caldocellum saccharolyticum gene that encodes a beta-glucosidase (bglA) and a polyadenylation sequence. Cre-mediated recombination is required to achieve expression of the reporter except in the small intestine where background activity is detected. (J:196052)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count