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The fluorescent ubiquitylation-based cell cycle indicator (Fucci2) is composed of two transgenes in which the mouse promoter driving ubiquitous expression of two fusion reporters. The mCherry and the ubiquitylation domains of human CDT1 fusion accumulates in the nuclei at G1 phase. The mVenus and the ubiquitylation domains of human GMNN fusion accumulates in the nuclei at S/G2/M phases. Chicken hypersensitive site 4 (cHS4) transcriptional insulator sequences flank the two transgenes. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:196795)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
