The transgene contains a BAC with a point mutation results in the amino acid substitution of alanine for histidine at position 1388 (H1388A). Lines 21 and 56 (with 6 and 3 copies of the transgene, respectively) were generated. (J:196346)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count