A PGK-neo cassette was inserted into the Hoxb2 intron, downstream of the translation start codon. Frt sites flanked the cassette with a loxP site following the 3' Frt site. Another loxP site was inserted into the Hoxb2 3' UTR downstream of the stop codon. Animals were crossed to Flpe deleter mice, excising the PGK-neo. (J:197162)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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