Expression of cre recombinase is driven r5-posterior rhombomere-specific Hoxb3 enhancer and the human the beta-globin minimal promoter. 19 founders were obtained, with 8 positive for cre. 3/8 showed the expected recombination pattern for the r5-posterior enhancer in PO brains. (J:193244)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count