A targeting vector was designed to insert a loxP site upstream of exon 2 and a frt- and loxP-flanked neomycin resistance (neo) cassette downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 2 floxed. (J:196943)
Basic Information
(C57BL/6J x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count