A targeting vector inserted a forward-oriented loxP site into the intron of Egr3 and a PGK-neo selection marker flanked by forward-oriented Frt sites and second forward-oriented loxP site (3' to the neo) into exon 2 immediately downstream of the TGA translation stop codon. The neo marker was excised by mating mice to CAG-FLPe mice. (J:196371)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count