A targeting vector inserted a forward-oriented loxP site into the intron of Egr3 and a PGK-neo selection marker flanked by forward-oriented Frt sites and second forward-oriented loxP site (3' to the neo) into exon 2 immediately downstream of the TGA translation stop codon. The neo marker was excised by mating mice to CAG-FLPe mice. (J:196371)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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