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A cytomegalovirus (CMV) promoter drives expression of the T cell receptor alpha and beta chain genes (Tcra and Tcrb) from the AHIII 12.2 T cell clone, which originated in a C57BL/6 mouse (H2b). This TCR recognizes the human self-peptide p1049 presented by the human HLA-A*0201 MHC molecule; it also recognizes the peptide p1058 (FAPGFFPYL) presented by the mouse MHC class I molecule H2-Db. (J:94077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
