A plasmid (pBT340, with the sequence pattB-pCA-GFP-pA-FRT5-pPGK-Flpo-pA) was injected into mouse embryos homozygous for a targeted mutation that had an Frt-flanked sequence. Several random insertions were obtained and analyzed for Flpo activity and ubiquitous GFP expression. When crossed to wild-type mice, all F1 progeny from one founder showed Flp-mediated excision. (J:171979)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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