A loxP site was inserted 5' of exon 2 and an Frt-Neo-Frt-loxP cassette was placed 3' of the same exon. The selection cassette was subsequently removed by crossing with mice expressing flp recombinase. Germline cre expression excised exon 2 and created a frame shift mutation. (J:194748)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Intragenic deletion
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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