Log In|Sign Up
EN
An IRES-EGFP-cre cassette and FRT-flanked neo marker were inserted into a BAC containing the Spo11 gene. A fragment containing the Spo11 sequence with 5 kb of upstream sequence, the IRES-EGFP-cre cassette and neo marker was isolated from the modified BAC and transfected into ES cells. Targeted ES cells were injected into blastocysts to generate transgenic animals. Founder information and line numbers are not available. (J:195191)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
