RMCE on KH2 cells inserted a cassette into the 3' UTR. The cassette contains the tetracycline responsive element (tetO) driving inducible expression of a C-terminal HA-tagged Yod1) with nucleotide substitutions that result in the amino acid substitution of serine for cysteine at position 160 (C160S). This mutation is expected to produce a catalytically inactivated product. (J:194608)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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