An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 48. An additional loxP site was inserted downstream of exon 52. Flp-mediated recombination removed the neo cassette and left exons 48 through 52 floxed. (J:195235)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count