The Krt15 promoter fragment was cloned into a plasmid with the cre/ERT2 sequence. The vector was injected into fertilized oocytes. Transgenic founders were produced and crossed to EYTP-reporter mice for analysis of recombination profiles. Founder line 12 which targeted bulge cells more specifically than other lines was established and used for further study. (J:195334)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count