A floxed neo cassette was inserted into exon 1. Western blot analysis confirmed reduced protein expression in the spleen. Cre-mediated recombination is required to restore full expression levels. (J:195018)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count