The coding region of the gene was flanked with loxP sites. Mice bearing the floxed allele were crossed with mice expressing Cre recombinase ubiquitously to produce animals in which the coding sequence has been deleted. (J:82809)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count