A loxP site was inserted upstream of exon 2. An FRT flanked gene trap cassette (splice acceptor, neo, IRES, GFP and polyadenylation sequence) with a 3' loxP site was targeted downstream of exon 3. (J:194195)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count