Two DNAse1 hypersensitive sites, termed "contracting element for recombination" or "Cer", were replaced with a loxP site flanked neomycin resistance gene cassette. Cre-mediated recombination was then used to remove the resistance cassette in mice. (J:193015)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count