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Lbr coding sequence with the second-to-last intron retained was inserted along with IRES-eGFP and placed under the control of tetO and a minimal promoter. Seven of 25 pups born from surrogate mothers were positive for the transgene by GFP genotyping. Five of seven transgenic lines expressed GFP in OSNs when crossed to OMP-IRES-tTA. The line chosen for analysis had an intermediate expression level and expressed GFP in most OSNs. (J:193207)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
