This mouse contains a bidirectional TetO-regulated gene inserted into a disabled Rosa26 locus. In one direction the tetO/CMV promoter drives expression of CFP (cerulean). In the other direction it drives Ngn3. Mice containing this allele can be used to inducibly express Ngn3 when interbred with either a rtTA or tTA transgene. (J:94077)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count