A 2.6 kb fragment of the Rlbp1 gene regulatory region (Rlbp1 promoter, exons 1 and 2 and intron 1) shown to drive Muller cell-specific gene expression was generated by PCR and cloned into a plasmid vector with a cre/ERT2 sequence separeted by IRES and EGFP-pA. The resulting 7 kb construct was linearized and injected into single-cell embryos. Founder information is not available. (J:154561, J:192243)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count