A 2.6 kb fragment of the Rlbp1 gene regulatory region (Rlbp1 promoter, exons 1 and 2 and intron 1) shown to drive Muller cell-specific gene expression was generated by PCR and cloned into a plasmid vector with a cre/ERT2 sequence separeted by IRES and EGFP-pA. The resulting 7 kb construct was linearized and injected into single-cell embryos. Founder information is not available. (J:154561, J:192243)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J x CBA
--
Insertion
--
--
--
20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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