A loxP site was inserted upstream of the coding sequence. An FRT-flanked neo cassette, loxP site and ECFP were inserted downstream of the open reading frame. Cre-mediated recombination removed the coding sequence and neo cassette. The ECFP remains intact. (J:193352)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count