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A combined EF1a-tTA and TetO-mCh/Rs1 transgene in a single construct (separated by a 2A ribosomal skip site) was inserted in the Gt(ROSA)26Sor locus. Rs1 is an engineered Gs-coupled G-protein coupled receptor in which an aspartic acid to alanine amino acid residue change at position 100 was made to generate serotonin-insensitive GPCR. (J:193162)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
