Exons 3 through 8 were replaced with the corresponding wild-type sequence with a C-terminal FLAG tag (6Y-FLAG), an FRT-flanked neo cassette, a loxP site and the corresponding sequence in which the six immunoreceptor tyrosine-based activation motif (ITAM) tyorsines mutated to encode phenylalanine followed by a C-terminal Myc tag (6F-Myc). (J:192915)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count