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A genomic clone containing the three linked fibrinogen genes was used to generate transgenic mice. Three lines of mice were created. Steady state levels of fibrinogen mRNA in liver of transgenic mice was shown to be 2.1-3.5 greater than in controls. A single copy of the transgene was inserted in this line. (J:118353)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
