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Exon 3 was replaced with a modified one with a premature stop codon. This mutation resembled the breakpoint of the t(3; X)(p25;p11) translocation. Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of the modified exon 3. Western blot anlaysis confirmed the absence of protein expression in the adult cortex. (J:192388)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
