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A 9.5 kb construct encoding SFTPC-cre/ERT2 (human surfactant associated protein C gene driving cre fused to a mutated estrogen receptor sequence; ERT2) was microinjected into mouse embryos to generated transgenic mice. Five founders were generated, but cre/ERT2 protein was stably expressed after tamoxifen injection by the progeny of only 2 lines, F42 and F67. These two lines were propagated for further experiments. Line F42 was entered as a representative line. (J:192111)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
