A loxP site was inserted upstream of exon 8. An FRT- and loxP site flanked neo cassette was inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette and left exon 8 floxed. (J:192126, J:192624)
Basic Information
(C57BL/6J x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count