Log In|Sign Up
EN
Exon 3 was replaced with a floxed neo cassette and a modified exon 3 in which an A to C and T to A transversion results in the amino acid substitutions of aspartic acid for alanine at position 2870 (A2870D) and lysine for asparagine at position 2875 (N2875K). These mutations result in a kinase dead protein. (J:191288)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
