A loxP site was inserted upstream of exon 5 and a loxP site and FRT flanked hygro cassette were inserted downstream of exon 5. Flp mediated recombination removed the hygro cassette. (J:191071)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count