Murine BAC clone RP23-446B12 was modified by the insertion of EGFP cDNA and a floxed neomycin resistance cassette after a translation initiation codon in exon 1. The 8 kb homologous recombination targeting vector was then recovered from the modified BAC and used to generate this allele. The selection cassette was then excised by transient cre expression. GFP expression was detected in thymic stromal cells. (J:189751)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x 129S6/SvEvTac)F1
Targeted
Insertion
--
1
2
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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