A targeting vector containing (from 5' to 3') a CAG promoter, a loxP-flanked transcription STOP cassette, the N-terminal 25 amino acid mitochondrial-targeting sequence of cytochrome c oxidase VIIIa (C8a), EGFP fused to a C-terminal triple V5 epitope, a bovine growth hormone 3' UTR, and a Frt-PGKneo-Frt cassette was inserted into the locus. (J:254093)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count