Homologous recombination inserted the cre recombinase sequence fused to a mutated tamoxifen-inducible estrogen receptor (cre/ERT2) into the translation initiation ATG codon of the neurogenin 3 gene located in a BAC. Three founder lines were obtained which all produced nearly identical patterns of cre expression. A generic line 1 was created as representative. (J:190530)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x (C57BL/6 x DBA/2)F1
--
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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