Homologous recombination inserted the cre recombinase sequence fused to a mutated tamoxifen-inducible estrogen receptor (cre/ERT2) into the translation initiation ATG codon of the neurogenin 3 gene located in a BAC. Three founder lines were obtained which all produced nearly identical patterns of cre expression. A generic line 1 was created as representative. (J:190530)
Basic Information
C57BL/6 x (C57BL/6 x DBA/2)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count